diff --git a/data/RNA16.react b/data/RNA16.react index beeb654..749faad 100644 --- a/data/RNA16.react +++ b/data/RNA16.react @@ -5542,80 +5542,81 @@ 120 NA >tRNA-asp -1 0.169603636 -2 0.06167405 -3 0.077092562 -4 0.138766612 -5 0.123348099 -6 0.107929587 -7 0.138766612 -8 0.169603636 -9 0.231277686 -10 0.246696198 -11 0.231277686 -12 0.308370248 -13 0.277533223 -14 0.277533223 -15 0.231277686 -16 0.477973884 -17 0.632159008 -18 0.817181157 -19 1.002203305 -20 0.832599669 -21 0.431718347 -22 0.354625785 -23 0.339207273 -24 0.354625785 -25 0.215859173 -26 0.277533223 -27 0.092511074 -28 0.107929587 -29 1.295155041 -30 0.308370248 -31 2.266521321 -32 1.942732561 -33 1.433921652 -34 1.433921652 -35 0.462555372 -36 0.493392397 -37 0.138766612 -38 0.416299835 -39 0.585903471 -40 0.107929587 -41 0.154185124 -42 0.092511074 -43 0.154185124 -44 0.215859173 -45 NA -46 0.262114711 -47 0.123348099 -48 0.092511074 -49 0.107929587 -50 0.092511074 -51 0.092511074 -52 0.169603636 -53 1.279736528 -54 0.508810909 -55 0.370044297 -56 0.169603636 -57 0.38546281 -58 0.308370248 -59 0.092511074 -60 0.107929587 -61 0.06167405 -62 0.138766612 -63 0.169603636 -64 0.123348099 -65 0.154185124 -66 0.077092562 -67 0.169603636 -68 0.138766612 -69 0.077092562 -70 0.046255537 -71 1.125551405 -72 0.277533223 -73 0.64757752 -74 1.819384462 +1 0.134 +2 0.044 +3 0.057 +4 0.114 +5 0.094 +6 0.09 +7 0.107 +8 0.131 +9 0.186 +10 0.198 +11 0.187 +12 0.256 +13 0.225 +14 0.221 +15 0.189 +16 0.387 +17 0.513 +18 0.665 +19 0.811 +20 0.672 +21 0.353 +22 0.292 +23 0.27 +24 0.281 +25 0.176 +26 0.228 +27 0.081 +28 0.084 +29 -999 +30 1.051 +31 -999 +32 -999 +33 1.83 +34 1.568 +35 1.163 +36 1.163 +37 0.376 +38 0.396 +39 0.113 +40 0.343 +41 0.472 +42 0.088 +43 0.119 +44 0.069 +45 0.12 +46 0.174 +47 0.208 +48 0.098 +49 0.08 +50 0.084 +51 0.074 +52 0.079 +53 0.132 +54 1.04 +55 0.412 +56 0.306 +57 0.136 +58 0.306 +59 0.253 +60 0.076 +61 0.081 +62 0.048 +63 0.107 +64 0.134 +65 0.099 +66 0.127 +67 0.06 +68 0.143 +69 0.111 +70 0.067 +71 0.035 +72 0.909 +73 0.224 +74 0.529 +75 1.475 >tRNAphe 1 0 diff --git a/data/RNA16_original_data/RNA16_format.py b/data/RNA16_original_data/RNA16_format.py index b2d0a1d..cd8a102 100644 --- a/data/RNA16_original_data/RNA16_format.py +++ b/data/RNA16_original_data/RNA16_format.py @@ -3,15 +3,23 @@ ##### import argparse parser = argparse.ArgumentParser(description='shape annotation') -parser.add_argument('--bpseq', type=str, default='BPseq', help='path to folder containing .bpseq files') -parser.add_argument('--seq', type=str, default='seq', help='path to folder containing .seq files') -parser.add_argument('--shape', type=str, default='shape', help='path to folder containing .shape files ') +#parser.add_argument('--bpseq', type=str, default='BPseq', help='path to folder containing .bpseq files') +#parser.add_argument('--seq', type=str, default='seq', help='path to folder containing .seq files') +#parser.add_argument('--shape', type=str, default='shape', help='path to folder containing .shape files ') +parser.add_argument('bpseq', type=str, default='BPseq', help='path to folder containing .bpseq files') +parser.add_argument('seq', type=str, default='seq', help='path to folder containing .seq files') +parser.add_argument('shape', type=str, default='shape', help='path to folder containing .shape files ') + args = parser.parse_args() DEBUG = True if DEBUG: print 'argparse args: ', args +# to run in Terminal: python RNA16_format.py --bpseq /home/montaser/ShaKer/data/RNA16_original_data/RNA16_dotbracket /home/montaser/ShaKer/data/RNA16_original_data/RNA16_sequences /home/montaser/ShaKer/data/RNA16_original_data/RNA16_shape +#/home/montaser/ShaKer/data/RNA16_original_data/RNA16_dotbracket +#/home/montaser/ShaKer/data/RNA16_original_data/RNA16_sequences +#/home/montaser/ShaKer/data/RNA16_original_data/RNA16_shape ######## @@ -51,15 +59,13 @@ def dump_fasta(se,dp,stringname): print res def dump_shape(shape,fname): - print shape + #print shape fnames = [ e[:e.find(".")] for e in fname ] - fix_data = lambda x: "\n".join([ str(i+1)+"\t"+e.strip() for i,e in enumerate( x.split("\n") ) if e.strip()>0 ]) + fix_data = lambda x: "\n".join([ str(i+1)+"\t"+e.strip() for i,e in enumerate( x.split("\n") ) if (e.strip()>0 and str(e)!="" ) ]) dataz = map(fix_data, shape) textlist = [">%s\n%s\n\n" % (name,data) for (name,data) in zip(fnames,dataz)] res = ''.join(textlist) dump("data.react",res) - print res + #print res -dump_fasta(seqs,bpseq,_) -dump_shape(shape,_) \ No newline at end of file diff --git a/data/RNA16_original_data/RNA16_sequences/23sRNA.seq b/data/RNA16_original_data/RNA16_sequences/23sRNA.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/5srRNA.seq b/data/RNA16_original_data/RNA16_sequences/5srRNA.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/ADDRSW.seq b/data/RNA16_original_data/RNA16_sequences/ADDRSW.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/GLYCFN.seq b/data/RNA16_original_data/RNA16_sequences/GLYCFN.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/MDLOOP.seq b/data/RNA16_original_data/RNA16_sequences/MDLOOP.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/R009.seq b/data/RNA16_original_data/RNA16_sequences/R009.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/RNAsep.seq b/data/RNA16_original_data/RNA16_sequences/RNAsep.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/TRP4.seq b/data/RNA16_original_data/RNA16_sequences/TRP4.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/Z-CIDGMP.seq b/data/RNA16_original_data/RNA16_sequences/Z-CIDGMP.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/Z-GLY.seq b/data/RNA16_original_data/RNA16_sequences/Z-GLY.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/ZHCV.seq b/data/RNA16_original_data/RNA16_sequences/ZHCV.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/adenin.seq b/data/RNA16_original_data/RNA16_sequences/adenin.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/p546.seq b/data/RNA16_original_data/RNA16_sequences/p546.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/sRNA.seq b/data/RNA16_original_data/RNA16_sequences/sRNA.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/tRNAPhe.seq b/data/RNA16_original_data/RNA16_sequences/tRNAPhe.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_sequences/trna-asp.seq b/data/RNA16_original_data/RNA16_sequences/trna-asp.seq old mode 100644 new mode 100755 diff --git a/data/RNA16_original_data/RNA16_shape/tRNA-asp.shape b/data/RNA16_original_data/RNA16_shape/tRNA-asp.shape old mode 100644 new mode 100755 index 9a7979e..94229b0 --- a/data/RNA16_original_data/RNA16_shape/tRNA-asp.shape +++ b/data/RNA16_original_data/RNA16_shape/tRNA-asp.shape @@ -1,74 +1,75 @@ -0.169603636 -0.06167405 -0.077092562 -0.138766612 -0.123348099 -0.107929587 -0.138766612 -0.169603636 -0.231277686 -0.246696198 -0.231277686 -0.308370248 -0.277533223 -0.277533223 -0.231277686 -0.477973884 -0.632159008 -0.817181157 -1.002203305 -0.832599669 -0.431718347 -0.354625785 -0.339207273 -0.354625785 -0.215859173 -0.277533223 -0.092511074 -0.107929587 -1.295155041 -0.308370248 -2.266521321 -1.942732561 -1.433921652 -1.433921652 -0.462555372 -0.493392397 -0.138766612 -0.416299835 -0.585903471 -0.107929587 -0.154185124 -0.092511074 -0.154185124 -0.215859173 --999 -0.262114711 -0.123348099 -0.092511074 -0.107929587 -0.092511074 -0.092511074 -0.169603636 -1.279736528 -0.508810909 -0.370044297 -0.169603636 -0.38546281 -0.308370248 -0.092511074 -0.107929587 -0.06167405 -0.138766612 -0.169603636 -0.123348099 -0.154185124 -0.077092562 -0.169603636 -0.138766612 -0.077092562 -0.046255537 -1.125551405 -0.277533223 -0.64757752 -1.819384462 \ No newline at end of file +0.134 +0.044 +0.057 +0.114 +0.094 +0.09 +0.107 +0.131 +0.186 +0.198 +0.187 +0.256 +0.225 +0.221 +0.189 +0.387 +0.513 +0.665 +0.811 +0.672 +0.353 +0.292 +0.27 +0.281 +0.176 +0.228 +0.081 +0.084 +-999 +1.051 +-999 +-999 +1.83 +1.568 +1.163 +1.163 +0.376 +0.396 +0.113 +0.343 +0.472 +0.088 +0.119 +0.069 +0.12 +0.174 +0.208 +0.098 +0.08 +0.084 +0.074 +0.079 +0.132 +1.04 +0.412 +0.306 +0.136 +0.306 +0.253 +0.076 +0.081 +0.048 +0.107 +0.134 +0.099 +0.127 +0.06 +0.143 +0.111 +0.067 +0.035 +0.909 +0.224 +0.529 +1.475 diff --git a/data/weeks194_orig/cellfreeGenes.dbn b/data/weeks194_orig/cellfreeGenes.dbn new file mode 100644 index 0000000..d9f4ba0 --- /dev/null +++ b/data/weeks194_orig/cellfreeGenes.dbn @@ -0,0 +1,1353 @@ +>T_1_1 +CAUAGCGCACAGACAGAUAAAAAUUACAGAGUACACAACAUCC +........................................... +>T_1_2 +CGCGUACAGGAAACACAGAAAAAAGCCCGCACCUGACAGUGCGGGCUUUUUUUUUCGACCAAAGGUAACGAGGUAACAACC +................................................................................. +>T_1_5 +AAUCUAUUCAUUAUCUCAAUCAGGCCGGGUUUGCUUU +..................................... +>T_2_1 +GACCGGUUACAUCCCCCUAACAAGCUGUUUAAAGAGAAAUACUAUC +.............................................. +>T_3_1 +ACCGCAGUGAGUGAGUCUGCAAAAAAAUGAAAUUGGGCAGUUGAAACCAGACGUUUCGCCCCUAUUACAGACUCACAACCACAUGAUGACCGAAUAUAUAGUGGAGACGUUUAG +.................................................................................................................. +>T_3_2 +UCGCCCUAUAAACGGGUAAUUAUACUGACACGGGCGAAGGGGAAUUUCCUCUCCGCCCGUGCAUUCAUCUAGGGGCAAUUUAAAAAAG +........................................................................................ +>T_3_3 +CCUCCCCAAAAGCCUGCCCGUGGGCAGGCCUGGGUAAAAAUAGGGUGCGUUGAAGAUAUGCGAGCACCUGUAAAGUGGCGGGGAUCACUCCCAUAAGCGCUAACUUAAGGGUUGUGGUAUUACGCCUGAUAUGAUUUAACGUGCCGAUGAAUUACUCUCACGAUAACUGGUCAGCAAUUCUGGCCCAUAUUGGUAAGCCCGAAGAACUGGAUAC +...................................................................................................................................................................................................................... +>T_4_1 +GCUUAGGGUCACUCGUGAGCGCUUACAGCCGUCAAAAACGCAUCUCACCGCUGAUGGCGCAAAUUCUUCAAUAGCUCGUAAAAAACGAAUUAUUCCUACACUAUAAUCUGAUUUUAACGAUGAUUCGUGCGGGGUAAAAUAGUAAAAACGAUCUAUUCACCUGAAAGAGAAAUAAAAA +.................................................................................................................................................................................. +>T_4_2 +CAGGACGGUUUACCGGGGAGCCAUAAACGGCUCCCUUUUCAUUG +............................................ +>T_5_1 +AUCACUACGUAACGAGUGCCGGCACAUUAACGGCGCUUAUUUGCACAAAUCCAUUGACAAAAGAAGGCUAAAAGGGCAUAUUCCUCGGCCUUUGAAUUGUCCAUAUAGAACACAUUUGGGAGUUGGACC +................................................................................................................................. +>T_5_2 +UCGCCAAUUUGCUGAAGCUUUGUGAAAAAGCCCGCGCAA +....................................... +>T_6_1 +AUUUUCACUGUUUUGAGCCAGAC +....................... +>T_6_2 +GCCUGUUAUGUAAUCAAACCGAAAUACGGAACCGAGAAUCUG +.......................................... +>T_6_4 +UAAACCCUGCCGGAUGCGAUGCUGACGCAUCUUAUCCGGCCUACAGAUUGCUGCGAAAUCGUAGGCCGGAUAAGGCGUUUACGCCGCAUCCGGCAAAAAUCCUUAAAUAUAAGAGCAAACCUGC +............................................................................................................................ +>T_6_6 +GUCAUUAGCAGCCUAAGUUAUGCGAAAAUGC +............................... +>T_7_1 +GCUUCGGGCGCGGUGUGAACAUUACGCUGGGCCUGCCCUUUAUUCGCACAUCAGUGGACCACGGCACCGCGCUUGAACUGGCGGGACGUGGCAAAGCCGAUGUCGGCAGUUUUAUUACGGCGCUUAAUCUCGCCAUCAAAAUGAUUGUUAACACCCA +............................................................................................................................................................. +>T_7_2 +CGAUGAUCAAUUCGCCCCGAGUGUGUAUUCAGGUUCAAAGCGUCUACAUUGAGGCUCAAUCUUCACCUGAUAAUGAACGUUACGUUUUUGCUUAUACCGUAACCAUACGCAAUCUGGGGCGAGCGCCAGUGCAGUUGUUGGGGCGUUACUGGCUGAUCACCAAUGGCAAUGGCCGUGAAACCGAAGUCCAGGGCGAAGGAGUGGUUGGCGUCCAGCCACUUAUCGCGCCUGGCGAAGAGUACCAGUACACCAGCGGUGCAAUCAUUGAAACCCCGCUGGGCACCAUGCAGGGUCACUACGAAAUGAUCGAUGAAAAUGGCGUCCCUUUCAGCAUCGACAUUCCCGUAUUCCGACUCGCCGUUCCCACACUCAUUCAUUAAAAGAAUAUGGCGACAUACCUUAUUGGCGACGUUCAUGGUUGUUACGAUGAACUGAUCGCAUUGCUGCAUAAAGUAGAAUUUACCCCUGGGAAAGAUACCCUCUGGCUGACGGGCGAUCUGGUCGCGCGCGGGCCGGGUUCGCUGGAUGUUCUGCGCUAUGUGAAAUCCUUAGGCGACAGCGUACGUCUGGUGCUGGGCAAUCACGAUCUGCAUCUGCUGG +........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_8_1 +UCAUACCUGUCAUUCAAUGCCGUGCCUAACACCACUGACGCUAUUCGGACAGGAUUAACACUAGCGUAGAGAUGACGAGUACGUUAGUCUCUGACCGUUUGUCACGCGCAACGUUACCGAUGAUGGAACAAUAAAAUCAACGU +............................................................................................................................................... +>T_8_2 +UUUGUUGAUUUACCACGUAAUCCGCAGUGCGGUUAAUUGAAAUGGAAAAAGU +.................................................... +>T_8_3 +UGGUUAAAACCCAACGUGUUGUGAUCACUCCCGGCGAGCCCGCCGGGAUUGGCCCGGACUUAGUUGUCCAGCUUGCACAGCGUGAGUGGCCGGUCGAACUGGUUGUUUGUGCCGAUGC +...................................................................................................................... +>T_9_1 +GUGGGAAAUUGUGGGGCAAAGUGGGAAUAAGGGGUGAGGCUGGC +............................................ +>T_9_11 +UUGUAGCGAUGCCUUUUGCAUCGUAUGAAUUUAAGAAGUUAAUGGCGUAAAGA +..................................................... +>T_9_13 +UAUGUCGCAGGCUGCUCUGAACACGCGAAACAGCGAAGAAGAGGUUUCUUCUCGCCGCAAUAAUGGAACGCGUCUGGCGGGGAUCCUUUUCCUGCUGACCGUUUUAACGACAGUGUUGGUGAGCGGCUGGGUCGUGUUGGGCUGGAUGGAAGAUGCGCAACGCCUGCCGCUCUCAAAGCUGGUGUUGACCGGUGAACGCCAUUACACACGUAAUGACGAUAUCCGGCAGUCGAUCCUGGCAUUGGGUGAGCCGGGUACCUUUAUGACCCAGGAUGUCAACAUCAUCCAGACGCAAAUAGAACAACGCCUGCCGUGGAUUAAGCAGGUGAGCGUCAGAAAGCAGUGGCCUGAUGAAUUGAAGAUUCAUCUGGUUGAAUAUGUGCCGAUUGCGCGGUGGAAUGAUCAACAUAUGGUAGACGCGGAAGGAAAUACCUUCAGCGUGCCGCCAGAACGCACCAGCAAGCAGGUGCUUCCAAUGCUGUAUGGCCCGGAAGGCAGCGCCAAUGAAGUGUUGCAGGGCUAUCGCGAAAUGGGGCAGAUGCUGGCAAAGGACAGAUUUACUCUGAAGGAAGCGGCGAUGACCGCGCGGCGUUCCUGGCA +........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_10_1 +CGAAGUAUCUCUCUGAUGAGACACAGUAUUUCUGCCCCGCAGGUCUGGAAGCGUCACAAGAGGCCAAUUUGCAGGCAUUAGUGCUGAAAGCAUGGACGACGUUAGGUUGCAAAGGAUGGGGACGUAUUGACGUUAUGCUGGACAGCGAUGGACAGUUUUAUCUGCUGGAAGCCAAUACCUCACCGGGUAUGACCAGCCACAGCCUGGUGCCGAUGGCGGCACGUCAGGCAGGUAUGAGCUUCUCGCAGUUGGUAGUACGAAUUCUGGAACUGGCGGACUAAU +.......................................................................................................................................................................................................................................................................................... +>T_10_3 +UUUUUAUGAGGCCGACGAUGAUUACGGCCUCAGGCGACAGGCACAAAUCGGAGAGAAACU +............................................................ +>T_10_4 +GAAUUGACUGGAAUUUGGGUUUCGAGGCUCUUUGUGCUAAACUGGCCCGCCGAAUGUAUAGUACACUUCGGUUGGAUAGGUAAUUUGGCGAGAUAAUACGAUGAUCAAACAAAGGACACUUAAACGUAUCGUUCAGGCGACGGGUGUCGGUUUACAUACCGGCAAGAAAGUCACCCUGACGUUACGCCCUGCGCCGGCCAACACCGGGGUCAUCUAUCGUCGCACCGACUUGAAUCCACCGGUAGAUUUCCCGGCCGAUGCCAAAUCUGUGCGUGAUACCAUGCUCUGUACGUGUCUGGUCAACGAGCAUGAUGUACGGAUUUCAACCGUAGAGCACCUCAAUGCUGCUCUCGCGGGCUUGGGCAUCGAUAACAUUGUUAUCGAAGUUAACGCGCCGGAAAUCCCGAUCAUGGACGGCAGCGCCGCUCCGUUUGUAUACCUGCUGCUUGACGCCGGUAUCGACGAGUUGAACUGCGCCAAAAAAUUUGUUCGCAUCAAAGAGACUGUUCGUGUCGAAGAUGGCGAUAAGUGGGCUGAAUUUAAGCCGUACAAUGGUUUUUCGCUGGAUUUCACCAUCGAUUUUAACCAUCCGGCUAUUGA +........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_11_1 +CCGCCGAAUGUAUAGUACACUUCGGUUGGAUAGGUAAUUUGGCGAGAUAAUACG +...................................................... +>T_11_2 +CGACAUUUAUACUGUCGUAUAAAAUUCGACUGGCAAAUCUGGCACUCUCUCCGGCCAGGUGAACC +................................................................. +>T_12_1 +CUAAAUACGUUUGAAUAUGAUCGGGAUGGCAAUAAC +.................................... +>T_12_2 +CAACAAUAAACCUUUACUUCAUUUUAUUAACUCCGCAACGCGGGGCGUUUGAGAUUUUAUU +............................................................. +>T_12_3 +AAGCUAACUGUUGAAGUAAAAGGCGCAGGAUU +................................ +>T_13_1 +ACAGGUUCCAGAAAACUCAACGUUAUUAGAUAGAUAAGGAAUAACCC +............................................... +>T_14_1 +GAUAGAACGACCCGGUGGUGGUUAGGGUAUUACUUCACAUACCCUAUGGAUUUCUGGGUGCAGCAAGGUAGCAAGCGCCAGAAUCCCCAGGAGCUUACAUAAGUAAGUGACUGGGGUGAGGGCGUGAAGCUAACGCCGCUGCGGCCUGAAAGACGACGGGUAUGACCGCCGGAGAUAAAUAUAUAGAGGUCAUG +.................................................................................................................................................................................................. +>T_14_2 +UUUUUCGUUUGCCGGAACAUCCGGCAAUU +............................. +>T_15_1 +GCGGUACUGGGCAUUUACCCUACAAACUGCUGUCUCACAGGAGCGUGAAGAGAAUCGCCUGCCGCACUAUGACAAUGAGAGCGAGGAGAACCGUC +............................................................................................... +>T_15_2 +AAAGUCAGCGCACGCGCUGCGCAUAAACGACACAAUGCCCGGUGAAUGAGAUUCCCGGG +........................................................... +>T_16_1 +CGUAAUUAUUUGGUUACAGGUCGUUAACCUCC +................................ +>T_17_1 +GUUAACGACAGGGUAGAAAGGUAGAAGUU +............................. +>T_18_1 +CUCAUUUUUCCCCCGAACAUGGGGAUCGAUAGUGCGUGUUAAGGAGAAGCAAC +..................................................... +>T_18_2 +UUACAGCCGUUCCAUCACGUUUACCACAGGCGGGAAAUGCUCCCGCCUUAU +................................................... +>T_19_1 +AUCAGGAUUGCACCAGUACAAGCAGCCUGAUGUUUGACGAGUAUUUAACUUGUUAUGAAUAACAUAGAAUAGCAGCCAUUCACUUUUUCUACGAAUCAGGAACCCUCC +............................................................................................................ +>T_19_2 +UCCAGCAUGGUUUGUCGGAUGCGGCGUG +............................ +>T_20_1 +CCGCCUGCUGCAGGAUUAUAUCAGCGGUAUGACCGACCUCUAUGCGUGGGAUGAAUACCGACGUCUGAUGGCCGUAGAACAAUAACCAGGCUUUUGUAAAGACGAACAAUAAAUUUUUACCUUUUGCAGAAACUUUAGUUCGGAACUUCAGGCUAUAAAACGAAUCUGAAGAACACAGCAAUUUUGCGUUAUCUGUUAAUCGAGACUGAAAUAC +...................................................................................................................................................................................................................... +>T_20_2 +UCUCCCUCAACCCCUUCCUGAAAACGG +........................... +>T_21_1 +GGACUUCCGAUCCAUUUCGUAUACACAGACUGGACGGAAGCGACAAUCUCACUUUGUGUAACAACACACACGUAUCGGCACAUAUUCCGGGGUGCCCUUUGGGGUCGGUAAUAUGGGAUACGUGGAGGCAUAACCCCAACUUUUAUAUAGAGGUUUUAAUC +................................................................................................................................................................. +>T_21_2 +UAAGGCUUGAUAACUCCCCCAAAAUAGUUCGAGUUGCAGAAAGGCGGCAAGCUCGAGAAUUCCCGGGAGCUUACAUCAGUAAGUGACCGGGAUGAGCGAGCGAAGAUAACGCAUCUGCGGCGCGAAAUAUGAAGGGGGAGAGCCCUUAUAGACCAGGUAGUACACGUUUGGUUAGGGGGCCUGCAUAUGGCCCCCUUUUUCACUUUUAUAUCUGUGCGGUUUAAUGCCGGGCAGAUCACAUCUCCGAGGAUUUUAGA +................................................................................................................................................................................................................................................................. +>T_22_1 +AGUAUUAAUUCAUUUCAAUCGUUGACAGUCUCAGGAAAGAAAC +........................................... +>T_22_2 +UUCCCGUGAUGGAUAAAUAAGGGUAAGAUUCCGCGUAAGUAUCGCGGGGGCGUAAGUCUGGUUAUAAGGCGUUAUUGUUGCAGGCAGUUUGGUCACGGCCAGCGCGCAGCAACCGGAGCGUACAAAAGUACGUGAGGAUGGCGAGCACUGCCCGGGGCCAAAAUGGCAAAUAAAAUAGCCUAAUAAUCCAGACGAUUACCCGUAAUAUGUUUAAUCAGGGCUAUACUUAGCACACUUCCACUGUGUGUGACUGUCUGGUCUGACUGAGACAAGUUUUCAAGGAUUCGUAAC 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+1 NA +2 NA +3 NA +4 NA +5 NA +6 NA +7 NA +8 NA +9 NA +10 NA +11 NA +12 NA +13 NA +14 NA +15 NA +16 NA +17 NA +18 NA +19 NA +20 NA +21 NA +22 NA +23 NA +24 NA +25 NA +26 NA +27 NA +28 NA +29 NA +30 NA +31 NA +32 NA + +>T_193_1 +1 NA +2 NA +3 NA +4 NA +5 NA +6 NA +7 NA +8 NA +9 NA +10 NA +11 NA +12 NA +13 NA +14 NA +15 NA +16 NA +17 NA +18 NA +19 NA +20 NA +21 NA +22 NA +23 NA +24 NA +25 NA +26 NA +27 NA +28 NA +29 NA +30 -0.04 +31 2.59 +32 1.56 +33 1.99 +34 0.57 +35 -0.16 +36 2.31 +37 -0.08 +38 -0.57 +39 -0.06 +40 -0.81 +41 0.06 +42 0.49 +43 0.16 +44 -0.04 +45 -0.11 +46 1.27 +47 -0.04 +48 0.19 +49 0.00 +50 0.40 +51 -0.09 +52 -0.07 +53 0.00 +54 0.12 +55 -0.16 +56 -0.04 +57 -0.05 +58 0.60 +59 0.88 +60 3.09 +61 -0.03 +62 0.43 +63 0.55 +64 -0.03 +65 0.85 +66 0.02 +67 0.11 +68 0.35 +69 -0.14 +70 -0.09 +71 0.48 +72 0.31 +73 0.40 +74 -0.25 +75 0.92 +76 0.23 +77 -0.44 +78 0.51 +79 -0.33 +80 0.88 +81 0.70 +82 -0.55 +83 0.71 +84 -0.30 +85 0.60 +86 0.20 +87 0.09 +88 0.76 +89 1.46 +90 -0.03 +91 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a/data/weeks194_orig/incellGenes.dbn b/data/weeks194_orig/incellGenes.dbn new file mode 100644 index 0000000..2f953cd --- /dev/null +++ b/data/weeks194_orig/incellGenes.dbn @@ -0,0 +1,495 @@ +>T_1_1 +CAUAGCGCACAGACAGAUAAAAAUUACAGAGUACACAACAUCC +........................................... +>T_1_2 +CGCGUACAGGAAACACAGAAAAAAGCCCGCACCUGACAGUGCGGGCUUUUUUUUUCGACCAAAGGUAACGAGGUAACAACC +................................................................................. +>T_1_5 +AAUCUAUUCAUUAUCUCAAUCAGGCCGGGUUUGCUUU +..................................... +>T_2_1 +GACCGGUUACAUCCCCCUAACAAGCUGUUUAAAGAGAAAUACUAUC +.............................................. +>T_3_1 +ACCGCAGUGAGUGAGUCUGCAAAAAAAUGAAAUUGGGCAGUUGAAACCAGACGUUUCGCCCCUAUUACAGACUCACAACCACAUGAUGACCGAAUAUAUAGUGGAGACGUUUAG +.................................................................................................................. +>T_3_2 +UCGCCCUAUAAACGGGUAAUUAUACUGACACGGGCGAAGGGGAAUUUCCUCUCCGCCCGUGCAUUCAUCUAGGGGCAAUUUAAAAAAG +........................................................................................ +>T_3_3 +CCUCCCCAAAAGCCUGCCCGUGGGCAGGCCUGGGUAAAAAUAGGGUGCGUUGAAGAUAUGCGAGCACCUGUAAAGUGGCGGGGAUCACUCCCAUAAGCGCUAACUUAAGGGUUGUGGUAUUACGCCUGAUAUGAUUUAACGUGCCGAUGAAUUACUCUCACGAUAACUGGUCAGCAAUUCUGGCCCAUAUUGGUAAGCCCGAAGAACUGGAUAC +...................................................................................................................................................................................................................... +>T_4_1 +GCUUAGGGUCACUCGUGAGCGCUUACAGCCGUCAAAAACGCAUCUCACCGCUGAUGGCGCAAAUUCUUCAAUAGCUCGUAAAAAACGAAUUAUUCCUACACUAUAAUCUGAUUUUAACGAUGAUUCGUGCGGGGUAAAAUAGUAAAAACGAUCUAUUCACCUGAAAGAGAAAUAAAAA +.................................................................................................................................................................................. +>T_4_2 +CAGGACGGUUUACCGGGGAGCCAUAAACGGCUCCCUUUUCAUUG +............................................ 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+........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_8_1 +UCAUACCUGUCAUUCAAUGCCGUGCCUAACACCACUGACGCUAUUCGGACAGGAUUAACACUAGCGUAGAGAUGACGAGUACGUUAGUCUCUGACCGUUUGUCACGCGCAACGUUACCGAUGAUGGAACAAUAAAAUCAACGU +............................................................................................................................................... +>T_8_2 +UUUGUUGAUUUACCACGUAAUCCGCAGUGCGGUUAAUUGAAAUGGAAAAAGU +.................................................... +>T_8_3 +UGGUUAAAACCCAACGUGUUGUGAUCACUCCCGGCGAGCCCGCCGGGAUUGGCCCGGACUUAGUUGUCCAGCUUGCACAGCGUGAGUGGCCGGUCGAACUGGUUGUUUGUGCCGAUGC +...................................................................................................................... +>T_9_1 +GUGGGAAAUUGUGGGGCAAAGUGGGAAUAAGGGGUGAGGCUGGC +............................................ +>T_9_11 +UUGUAGCGAUGCCUUUUGCAUCGUAUGAAUUUAAGAAGUUAAUGGCGUAAAGA +..................................................... +>T_9_13 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+........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_10_1 +CGAAGUAUCUCUCUGAUGAGACACAGUAUUUCUGCCCCGCAGGUCUGGAAGCGUCACAAGAGGCCAAUUUGCAGGCAUUAGUGCUGAAAGCAUGGACGACGUUAGGUUGCAAAGGAUGGGGACGUAUUGACGUUAUGCUGGACAGCGAUGGACAGUUUUAUCUGCUGGAAGCCAAUACCUCACCGGGUAUGACCAGCCACAGCCUGGUGCCGAUGGCGGCACGUCAGGCAGGUAUGAGCUUCUCGCAGUUGGUAGUACGAAUUCUGGAACUGGCGGACUAAU +.......................................................................................................................................................................................................................................................................................... +>T_10_3 +UUUUUAUGAGGCCGACGAUGAUUACGGCCUCAGGCGACAGGCACAAAUCGGAGAGAAACU +............................................................ +>T_10_4 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+........................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_10_1 +CGAAGUAUCUCUCUGAUGAGACACAGUAUUUCUGCCCCGCAGGUCUGGAAGCGUCACAAGAGGCCAAUUUGCAGGCAUUAGUGCUGAAAGCAUGGACGACGUUAGGUUGCAAAGGAUGGGGACGUAUUGACGUUAUGCUGGACAGCGAUGGACAGUUUUAUCUGCUGGAAGCCAAUACCUCACCGGGUAUGACCAGCCACAGCCUGGUGCCGAUGGCGGCACGUCAGGCAGGUAUGAGCUUCUCGCAGUUGGUAGUACGAAUUCUGGAACUGGCGGACUAAU +.......................................................................................................................................................................................................................................................................................... +>T_10_3 +UUUUUAUGAGGCCGACGAUGAUUACGGCCUCAGGCGACAGGCACAAAUCGGAGAGAAACU +............................................................ +>T_10_4 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+.................................................................................................................................................. +>T_131_226 +CGCCUCGUUUUCCAGGUUUGUUGGAGAAAGAAA +................................. +>T_131_227 +AGCUUAGUACCAAAGAGAGGACACA +......................... +>T_131_228 +CCGGAUCACAGGUUAAGGUUUUACUGAGAAGGAUAAGGUC +........................................ +>T_132_230 +UCAGGUCAUUGAGCGAUUGAGAGGUUGAAACA +................................ +>T_133_241 +UGGUUCUCCGUUAAGUAAGGCCAAACGUUUUAACUUAAAUGUCAAACUAAACUCGUAGAGUUUUGGACAAUCCUGAAUUAACAACGGAGUAUUUCC +................................................................................................ +>T_133_242 +ACGCCUAAAAGAUAAACGAGGAAACAA +........................... +>T_133_243 +GCCUAAGGGUUAAUACCAAAGUCCCGUGCUCUCUCCUGAAGGGGAGAGCACUAUAGUAAGGAAUAUAGCC +...................................................................... +>T_146_258 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+................................................................................................................................................................. +>T_151_277 +UUUACCAACACUACUACGUUUUAACUGAAACAAACUGGAGACUGUC +.............................................. +>T_151_278 +UAAGCGUUGCUUUUAUUUAAAGAGCAAUAUCAGAACGUUAACUAAAUAGAGGCAUUGUGCU +............................................................. +>T_151_281 +CGUCUGGCGGCUUGCCUUAGGGCAGGCCGCAAGGCAUUGAGGAGAAGCUC +.................................................. +>T_151_282 +ACAGGUUAUUUCGUAGAGGAUUUAAG +.......................... +>T_151_283 +CGCCUUAAUCGGAGGGUGAU +.................... +>T_153_286 +AUAAAAAAUGUCAUACUCAAAAUCAUUCAAACUGUAUCAAGAUGGCAAGAGAAUGAAUCCCGAUGAGCUUACUGUAGUAAGUGAUUCAGGUGAAAGAAUGCAGCCAACACAGAGACAGAUUGAAGGAUGAAGAGU +....................................................................................................................................... +>T_154_288 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+............................................................................................................................................................................................................................................................................................................................................................................................................................ +>T_176_333 +UCGCAGUUAUCUUUUUAACGCAUUCGCUUACGUAUAAACUUAUUCUGAUAUUCAGGAACAAUUUAA +.................................................................. +>T_176_334 +GCCAACCCUUCCGGUUGCAGCCUGAGAAAUCAGGCUGAUGGCUGGUGACUUUUUAGUCACCAGCCUUUUUGCGCUGUAAGGCGCCAGUAGCGUUUCACACUGUUUGACUACUGCUGUGCCUUUCAAUGCUUGUUUCUAUCGACGACUUAAUAUACUGCGACAGGACGUCCGUUCUGUGUAAAUCGCAAUGAAAUGGUUUAAGCGUGAUAGCAACAGGCAUUGCGGAAAGUGUUCCAUUUUCCGGUCAACAAAAUAGUGUUGCACAAACUGUCCGCUCAAUGGACAGAUGGGUCGACUUGUCAGCGAGCUGAGGAACCCU +............................................................................................................................................................................................................................................................................................................................... +>T_176_335 +UUCUCGCUCAAACAGGUCACUGCUGUCGGGUUAAAACCCGGCAGCGGAUUGUGCUAACUCCGACGGGAGCAAAUCC +............................................................................ +>T_178_338 +ACCACCACAUAACUAUGGAGCAUCUGCAC +............................. +>T_180_341 +CCCUUCCAGAAUUCGAUAAAUCUCUGGUUUAUUGUGCAGUUUAUGGUUCCAAAAUCGCCUUUUGCUGUAUAUACUCACAGCAUAACUGUAUAUACACCCAGGGGGCGGA +............................................................................................................. +>T_184_346 +UCCGCGCACGACACUGAACAUACGAAUUUAAGGAAUAAAGAUA +........................................... +>T_186_349 +AUGUGUACAAUUGAGACGUAUCGUGCGCAAUUUUUUCAGAAUCGAAAGGUUCAAAGUACAAAUAAGCAUAUAAGGAAAAGAGAGA +..................................................................................... +>T_186_350 +GGUUUCGGGCUGUUUUUUUACACGGGGAGCCAGCGAUCCUGCGUUCCCCGCUGAUCUAUUUAGAGGGUUAUACGC +........................................................................... +>T_186_351 +CGGCGUAGCGUCUGAAGCGUGGAGUCAUAUCCUCUGGCGUCGAAAGACAACAGGGAUCACCGCAUAACAAAUAUGGAGCACAAAC +..................................................................................... +>T_188_357 +UCGGUCACGGUCCAUUAAUACGACUUUGAGAGGAUAAGGUA +......................................... +>T_191_361 +UUGCGUCAGGCAAGGCUGUUAUUGCCGGAUGCGGCGUGAACGCCUUAUCCGACCUACACAGCACUGAACUCGUAGGCCUGAUAAGACACAACAGCGUCGCAUCAGGCGCUGCGGUGUAUACCUGAUGCGUAUUUAAAUCCACCACAAGAAGCCCCAUUU +............................................................................................................................................................... diff --git a/data/weeks194_orig/kasugamycinreacts.react b/data/weeks194_orig/kasugamycinreacts.react new file mode 100644 index 0000000..50624ce --- /dev/null +++ b/data/weeks194_orig/kasugamycinreacts.react @@ -0,0 +1,16418 @@ +>T_1_1 +1 NA +2 NA +3 NA +4 NA +5 NA +6 NA +7 NA +8 NA +9 NA +10 NA +11 NA +12 NA +13 NA +14 NA +15 NA +16 NA +17 NA +18 NA +19 NA +20 NA +21 NA +22 NA +23 NA +24 NA +25 NA +26 NA +27 NA +28 NA +29 NA +30 NA +31 NA +32 NA +33 NA +34 NA +35 NA +36 NA +37 NA +38 NA +39 NA +40 NA +41 NA +42 NA +43 NA + +>T_1_2 +1 NA +2 NA +3 NA +4 NA +5 NA +6 NA +7 NA +8 NA +9 NA +10 NA +11 NA +12 NA +13 NA +14 NA +15 NA +16 NA +17 NA +18 NA +19 NA +20 NA +21 NA +22 NA +23 NA +24 NA +25 NA +26 NA +27 NA +28 NA +29 NA +30 NA +31 NA +32 NA +33 NA +34 NA +35 NA +36 NA +37 NA +38 NA +39 NA +40 NA +41 NA +42 NA +43 NA +44 NA +45 NA +46 NA +47 NA +48 NA +49 NA +50 NA +51 NA +52 NA +53 NA +54 NA +55 NA +56 NA +57 NA +58 NA +59 NA +60 NA +61 NA +62 NA +63 NA +64 NA +65 NA +66 NA +67 NA +68 NA +69 NA +70 NA +71 NA +72 NA +73 NA +74 NA +75 NA +76 NA +77 NA +78 NA +79 NA +80 NA +81 NA + +>T_1_5 +1 NA +2 NA +3 NA +4 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+146 0.44 +147 2.11 +148 5.40 +149 0.53 +150 1.11 +151 -0.24 +152 0.67 +153 0.54 +154 -0.00 +155 0.34 +156 1.26 +157 0.75 +158 2.12 +159 1.27 + diff --git a/extract_genes.py b/extract_genes.py new file mode 100644 index 0000000..40b657e --- /dev/null +++ b/extract_genes.py @@ -0,0 +1,130 @@ +import collections +path="/home/montaser/ShaKer/data/weeks194_orig/" + +#for genes +def extractgenes(): + endIdxG = 0 + i = 0 + filew = openfile("kasugamycinGenes.dbn", "w") + filer = openfile("genes.txt", "r") + extractfilerInfo(filer, filew, endIdxG, i)# extract information from read file + + +def openfile(filename, type): + if type == "w": + file = open(path + filename, "w") # write into a file + else: file = open(path + filename, "r") # read a file + return file + +def extractfilerInfo(filer, filew, endIdxG, i, reactdict = None): + with filer as g: # read readable file + g.next() + for e in g: + if "," in e: # all the lines with "," are interesting + name, Gstart, Gend, Tstart, Tend, idx = e.strip().split(',')[0:6] + assert (int(Gend) - int(Gstart)) == (int(Tend) - int(Tstart)) + l = extractLSeq(idx) + if reactdict == None: endIdxG, i = extractTranscriptomes(idx, Tstart, Tend, filew, endIdxG, i) + else: endIdxG, i, reactdict = computereact(idx, Tstart, Tend, l, filew, endIdxG, i, reactdict) + +def extractTranscriptomes(idx, Tstart, Tend, filew, endIdxG, i): + cutoff = 20 + structure = "" + filer = openfile("kasugamycin.dbn", "r") + with filer as D: + for d in D: + if ">" in d: + namesidx = d.strip().split('_')# CONTAINS NAME AND INDEX + if namesidx[len(namesidx)-1] == idx: + i = i + 1 + seq = D.next() + if endIdxG == 0: # write the first transcript + startIdxT = endIdxG + if len(seq[startIdxT: int(Tstart) - 1]) >= cutoff: + structure = makeStructure(len(seq[startIdxT: int(Tstart) - 1])) + filew.write(">%s\n%s\n%s\n" % ("T_" + idx + "_" + str(i), seq[startIdxT: int(Tstart) - 1], structure)) + else: # write the rest transcript + startIdxT = endIdxG + 1 + if len(seq[startIdxT - 1: int(Tstart) - 1])>= cutoff: + structure = makeStructure(len(seq[startIdxT - 1: int(Tstart) - 1])) + filew.write(">%s\n%s\n%s\n" % ("T_" + idx + "_" + str(i), seq[startIdxT - 1: int(Tstart) - 1], structure)) + endIdxG = int(Tend) + if i == len(namesidx) - 1: # write the last transcript + if len(seq[endIdxG: ]) - 1 >= cutoff: + structure = makeStructure(len(seq[endIdxG: ]) -1) + filew.write(">%s\n%s%s\n" % ("T_" + idx + "_" + str(i+1), seq[endIdxG: ], structure)) + endIdxG = 0 + i = 0 + break + return (endIdxG, i) + +def makeStructure(lseq): + struct = "" + for k in range(lseq): + struct = struct + "." + return struct + + +#for reactivities +def extractreacts(): + endIdxG = 0 + i = 0 + l = 0 + react = "" + reactdict = {} + filew = openfile("kasugamycinreacts.react", "w") + filer = openfile("genes.txt", "r") + extractfilerInfo(filer, filew, endIdxG, i, reactdict)# extract information from read file + + +def extractLSeq(idx): + with open(path + "kasugamycin.dbn", "r") as C: + for c in C: + if ">" in c: + namesidx = c.strip().split('_') + indx1 = namesidx[len(namesidx)-1] + if indx1 == idx: + seq = C.next() + l = len(seq) + return l + +def computereact(idx, Tstart, Tend, l, filew, endIdxG, i, reactdict): + cutoff = 20 + filer = openfile("kasugamycin.react", "r") + with filer as D: + for d in D: + if ">" in d: + namesidx = d.strip().split('_')# contains name and index + if namesidx[len(namesidx)-1] == idx: + i = i + 1 + for d in D: + if ">" not in d: + index, react = d.strip().split(' ')[0:2] # contains index and reactivity + reactdict[int(index)] = react# contains reactivity + else: break + reactdict = collections.OrderedDict(sorted(reactdict.items()))# sort reactdict + text1= "" + if endIdxG == 0: # Index of the first transcript + for k in range (endIdxG - 1, int(Tstart) - 2): + text1 = text1 + str(k - endIdxG + 2) + " " + reactdict.values()[k + 1] + "\n" + else: # Index of the rest transcripts + for k in range (endIdxG, int(Tstart) - 1): + text1 = text1 + str(k - endIdxG + 1) + " " + reactdict.values()[k] + "\n" + if int(Tstart) - endIdxG - 1 >= cutoff: + filew.write(">%s\n%s\n" % ("T_" + idx + "_" + str(i), text1)) # write the transcripts + endIdxG = int(Tend) + if i == len(namesidx) - 1: # write the last transcript + text1 = "" + for k in range (endIdxG, l - 1): + text1 = text1 + str(k - endIdxG + 1) + " " + reactdict.values()[k] + "\n" + if l - endIdxG - 1 >= cutoff: + filew.write(">%s\n%s\n" % ("T_" + idx + "_" + str(i+1), text1)) + endIdxG = 0 + i = 0 + break + + return (endIdxG, i, reactdict) + + + + diff --git a/notebooks/01_intro.ipynb b/notebooks/01_intro.ipynb index 10ad32a..8189bb5 100644 --- a/notebooks/01_intro.ipynb +++ b/notebooks/01_intro.ipynb @@ -2,10 +2,7 @@ "cells": [ { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# quick demo / data inspection" ] @@ -18,10 +15,7 @@ "classes": [], "id": "", "n": "1" - }, - "collapsed": false, - "deletable": true, - "editable": true + } }, "outputs": [], "source": [ @@ -39,10 +33,7 @@ }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# Load data" ] @@ -51,7 +42,6 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": false, "scrolled": true }, "outputs": [], @@ -72,9 +62,7 @@ { "cell_type": "code", "execution_count": null, - "metadata": { - "collapsed": false - }, + "metadata": {}, "outputs": [], "source": [ "import simushape as sim\n", @@ -95,7 +83,6 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": false, "scrolled": false }, "outputs": [], @@ -133,7 +120,7 @@ "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython2", - "version": "2.7.12" + "version": "2.7.11" } }, "nbformat": 4, diff --git a/notebooks/03_accessibility.ipynb b/notebooks/03_accessibility.ipynb index 6c336b0..b65df01 100644 --- a/notebooks/03_accessibility.ipynb +++ b/notebooks/03_accessibility.ipynb @@ -2,10 +2,7 @@ "cells": [ { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# comparison of accessibility of nucleotides in the sequences" ] @@ -18,10 +15,7 @@ "classes": [], "id": "", "n": "1" - }, - "collapsed": false, - "deletable": true, - "editable": true + } }, "outputs": [ { @@ -53,10 +47,7 @@ }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# Load data" ] @@ -65,9 +56,6 @@ "cell_type": "code", "execution_count": 2, "metadata": { - "collapsed": false, - "deletable": true, - "editable": true, "scrolled": true }, "outputs": [ @@ -107,10 +95,7 @@ }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# train predict" ] @@ -118,11 +103,7 @@ { "cell_type": "code", "execution_count": 3, - "metadata": { - "collapsed": false, - "deletable": true, - "editable": true - }, + "metadata": {}, "outputs": [ { "name": "stdout", @@ -135,6 +116,12 @@ "name": "stderr", "output_type": "stream", "text": [ + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", "../rna_tools/rnaplfold.py:31: FutureWarning: comparison to `None` will result in an elementwise object comparison in the future.\n", " if react == None:\n" ] @@ -182,9 +169,7 @@ { "cell_type": "code", "execution_count": 4, - "metadata": { - "collapsed": true - }, + "metadata": {}, "outputs": [], "source": [ "from rna_tools.sukosd import sukosd\n", @@ -196,9 +181,7 @@ { "cell_type": "code", "execution_count": 5, - "metadata": { - "collapsed": false - }, + "metadata": {}, "outputs": [], "source": [ "from scipy.stats import spearmanr as spear\n", @@ -210,10 +193,7 @@ }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# Visualize " ] @@ -222,9 +202,6 @@ "cell_type": "code", "execution_count": 6, "metadata": { - "collapsed": false, - "deletable": true, - "editable": true, "scrolled": false }, "outputs": [ @@ -232,18 +209,18 @@ "data": { "text/html": [ "
\n", - "\n", "\n", " \n", @@ -257,26 +234,26 @@ " \n", " \n", " \n", - " \n", - " \n", + " \n", + " \n", " \n", " \n", " \n", " \n", - " \n", - " \n", + " \n", + " \n", " \n", " \n", " \n", " \n", - " \n", - " \n", + " \n", + " \n", " \n", " \n", " \n", " \n", - " \n", - " \n", + " \n", + " \n", " \n", " \n", " \n", @@ -285,10 +262,10 @@ ], "text/plain": [ " suko shaker shaker_str\n", - "ADDRSW 0.956379 0.981441 0.983979\n", - "GLYCFN 0.308677 0.558365 0.258756\n", - "tRNAphe 0.871030 0.930402 0.945657\n", - "mean 0.712029 0.823403 0.729464" + "ADDRSW 0.986336 0.983577 0.983979\n", + "GLYCFN 0.228127 0.554957 0.258756\n", + "tRNAphe 0.936375 0.914695 0.945657\n", + "mean 0.716946 0.817743 0.729464" ] }, "execution_count": 6, @@ -308,9 +285,7 @@ { "cell_type": "code", "execution_count": null, - "metadata": { - "collapsed": true - }, + "metadata": {}, "outputs": [], "source": [] } @@ -331,7 +306,7 @@ "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython2", - "version": "2.7.12" + "version": "2.7.11" } }, "nbformat": 4, diff --git a/notebooks/04_accuracy.ipynb b/notebooks/04_accuracy.ipynb index dac79e4..c1d68f0 100644 --- a/notebooks/04_accuracy.ipynb +++ b/notebooks/04_accuracy.ipynb @@ -1,30 +1,25 @@ { "cells": [ { - "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], "source": [ "# meassurement of the accuracy \n", "\n", - "accuracy is \n", - "mean{ p in dotplot @ i,j | i,j in real_structure }" + "#accuracy is mean{ p in dotplot @ i,j | i,j in real_structure }" ] }, { "cell_type": "code", - "execution_count": 1, + "execution_count": 2, "metadata": { "attributes": { "classes": [], "id": "", "n": "1" - }, - "collapsed": false, - "deletable": true, - "editable": true + } }, "outputs": [ { @@ -36,7 +31,7 @@ "" ] }, - "execution_count": 1, + "execution_count": 2, "metadata": {}, "output_type": "execute_result" } @@ -56,21 +51,15 @@ }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# Load data" ] }, { "cell_type": "code", - "execution_count": 2, + "execution_count": 3, "metadata": { - "collapsed": false, - "deletable": true, - "editable": true, "scrolled": true }, "outputs": [ @@ -78,7 +67,6 @@ "name": "stdout", "output_type": "stream", "text": [ - "data for 'tRNA-asp' is corrupted, ignoring...\n", "ADDRSW \t121\n", "GLYCFN \t205\n", "tRNAphe \t76\n", @@ -86,6 +74,7 @@ "ZHCV \t95\n", "Z-CIDGMP-1 \t135\n", "adenin \t71\n", + "tRNA-asp \t75\n", "23sRNA \t2904\n", "p564 \t155\n", "srRNA \t120\n", @@ -110,28 +99,48 @@ }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# train predict" ] }, { "cell_type": "code", - "execution_count": 3, - "metadata": { - "collapsed": false, - "deletable": true, - "editable": true - }, + "execution_count": 4, + "metadata": {}, "outputs": [ { - "name": "stdout", + "name": "stderr", "output_type": "stream", "text": [ - "data for 'tRNA-asp' is corrupted, ignoring...\n" + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n" ] } ], @@ -140,10 +149,10 @@ "from rna_tools.rnaplfold import rnaplfold\n", "\n", "data = getdata()\n", - "model = sim.make_model(data,['23sRNA','R009'])\n", + "model = sim.make_model(data,['23sRNA','R009'],sim.make_forestregressor())\n", "data.pop(\"23sRNA\")\n", "data.pop(\"R009\")\n", - "keys = data.keys()[:3]\n", + "keys = data.keys()\n", "\n", "def get_str(seq):\n", " for _, data_seq, db in data.values():\n", @@ -153,188 +162,196 @@ "\n", "# acc_calculator needs seq struct rea\n", "predictions = { k: (data[k][1],data[k][2],sim.predict(model,data[k][1], seq_to_db_function=get_str)) for k in keys }\n", + "\n", + "shaker_plain = { k: (data[k][1],data[k][2],sim.predict(model,data[k][1])) for k in keys }\n", "\n" ] }, { "cell_type": "code", "execution_count": null, - "metadata": { - "collapsed": true, - "deletable": true, - "editable": true - }, + "metadata": {}, "outputs": [], "source": [] }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# get accuracy" ] }, { "cell_type": "code", - "execution_count": 4, - "metadata": { - "collapsed": false, - "deletable": true, - "editable": true - }, + "execution_count": 5, + "metadata": {}, "outputs": [ { "name": "stderr", "output_type": "stream", "text": [ "../rna_tools/rnaplfold.py:31: FutureWarning: comparison to `None` will result in an elementwise object comparison in the future.\n", - " if react == None:\n" + " if react == None:\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n", + "/home/montaser/miniconda2/lib/python2.7/site-packages/sklearn/utils/validation.py:395: DeprecationWarning: Passing 1d arrays as data is deprecated in 0.17 and will raise ValueError in 0.19. Reshape your data either using X.reshape(-1, 1) if your data has a single feature or X.reshape(1, -1) if it contains a single sample.\n", + " DeprecationWarning)\n" ] } ], "source": [ "from rna_tools.sukosd import sukosd\n", "from rna_tools.rna_accuracy import get_structure_accuracy\n", + "import simushape as sim\n", "\n", "acc_shaker = {k: get_structure_accuracy(*predictions[k]) for k in keys} \n", - "\n", - "\n", + "acc_shaker_plain = {k: get_structure_accuracy(*shaker_plain[k]) for k in keys} \n", "predictions_suko = { k: (data[k][1],data[k][2],sukosd(data[k][2])) for k in keys }\n", - "\n", "acc_suko = {k: get_structure_accuracy(*predictions_suko[k]) for k in keys} \n", - "\n", "acc_real = {k: get_structure_accuracy(data[k][1],data[k][2],data[k][0]) for k in keys}\n", - "\n", - "\n", "acc_noshape = {k: get_structure_accuracy(data[k][1],data[k][2],None) for k in keys}\n", "\n", + "\n", + "predictions_suko_predicted = { k: (data[k][1],data[k][2],sim.predict_Suko(data[k][1])) for k in keys }\n", + "acc_suko_predicted = {k: get_structure_accuracy(*predictions_suko_predicted[k]) for k in keys} \n", "\n" ] }, { "cell_type": "code", "execution_count": null, - "metadata": { - "collapsed": true, - "deletable": true, - "editable": true - }, + "metadata": {}, "outputs": [], "source": [] }, { "cell_type": "markdown", - "metadata": { - "deletable": true, - "editable": true - }, + "metadata": {}, "source": [ "# Visualize " ] }, { "cell_type": "code", - "execution_count": 5, + "execution_count": 6, "metadata": { - "collapsed": false, - "deletable": true, - "editable": true, "scrolled": false }, "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + " suko shaker shaker_plain real no_shape \\\n", + "ADDRSW 0.905611 0.995021 0.994965 0.987444 0.872423 \n", + "GLYCFN 0.971953 0.976495 0.369785 0.000000 0.565605 \n", + "tRNAphe 0.996341 0.995508 0.600237 0.995362 0.504352 \n", + "RNAsep 0.753366 0.697046 0.684829 0.676623 0.530544 \n", + "ZHCV 0.900271 0.895726 0.897014 0.533042 0.744884 \n", + "Z-CIDGMP-1 0.828740 0.908340 0.745593 0.759976 0.727020 \n", + "adenin 0.997740 0.991421 0.991458 0.981553 0.871697 \n", + "tRNA-asp 0.914232 0.843627 0.497580 0.550157 0.518002 \n", + "p564 0.881836 0.905980 0.365788 0.904553 0.625162 \n", + "srRNA 0.935614 0.908478 0.279121 0.849606 0.274786 \n", + "ZGLY 0.847167 0.974793 0.456047 0.862487 0.482860 \n", + "MDLOOP 0.999321 0.998109 0.998327 0.991718 0.988975 \n", + "5srRNA 0.878293 0.972865 0.261391 0.252744 0.260634 \n", + "TRP5 0.912227 0.913598 0.902040 0.821419 0.838098 \n", + "mean 0.908765 0.926929 0.646012 0.726192 0.628932 \n", + "\n", + " acc_suko_predicted \n", + "ADDRSW 0.990753 \n", + "GLYCFN 0.599106 \n", + "tRNAphe 0.968698 \n", + "RNAsep 0.372281 \n", + "ZHCV 0.894001 \n", + "Z-CIDGMP-1 0.755861 \n", + "adenin 0.988100 \n", + "tRNA-asp 0.497472 \n", + "p564 0.734297 \n", + "srRNA 0.270095 \n", + "ZGLY 0.426588 \n", + "MDLOOP 0.998010 \n", + "5srRNA 0.263125 \n", + "TRP5 0.902021 \n", + "mean 0.690029 \n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "/home/montaser/miniconda2/lib/python2.7/site-packages/matplotlib/cbook/deprecation.py:106: MatplotlibDeprecationWarning: Adding an axes using the same arguments as a previous axes currently reuses the earlier instance. In a future version, a new instance will always be created and returned. Meanwhile, this warning can be suppressed, and the future behavior ensured, by passing a unique label to each axes instance.\n", + " warnings.warn(message, mplDeprecation, stacklevel=1)\n" + ] + }, { "data": { - "text/html": [ - "
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\n", "text/plain": [ - " suko shaker real no_shape\n", - "ADDRSW 0.991740 0.992601 0.987444 0.872423\n", - "GLYCFN 0.885658 0.957059 0.000000 0.565605\n", - "tRNAphe 0.993797 0.993299 0.995362 0.504352\n", - "mean 0.957065 0.980986 0.660935 0.647460" + "" ] }, - "execution_count": 5, "metadata": {}, - "output_type": "execute_result" + "output_type": "display_data" } ], "source": [ "import pandas\n", "import numpy as np\n", - "index= ['suko',\"shaker\",'real',\"no_shape\"]\n", - "data = map(lambda x: [x[k] for k in keys] ,[acc_suko, acc_shaker, acc_real, acc_noshape])\n", + "import matplotlib.pyplot as plt\n", + "index= ['suko',\"shaker\",\"shaker_plain\",'real',\"no_shape\", \"acc_suko_predicted\"]\n", + "data = map(lambda x: [x[k] for k in keys] ,[acc_suko, acc_shaker,acc_shaker_plain, acc_real, acc_noshape, acc_suko_predicted])\n", "map(lambda x:x.append(np.mean(x)),data)\n", - "pandas.DataFrame(data, columns=keys+['mean'], index=index).T" + "df = pandas.DataFrame(data, columns=keys+['mean'], index=index).T\n", + "print df\n", + "\n", + "fig = plt.figure(figsize=(8,6))\n", + "plt.boxplot(data, 0, 'rs', 1)\n", + "plt.xticks([y+1 for y in range(len(data))], ['suko',\"shaker\",\"shaker_plain\",'real',\"no_shape\",\"acc_suko_predicted\"])\n", + "plt.xlabel(\"Comparison of accuracies\")\n", + "plt.ylim((0,1))\n", + "ax = fig.add_subplot(1, 1, 1)\n", + "major_ticks = np.arange(0, 1, 0.05)\n", + "minor_ticks = np.arange(0, 1, 0.05)\n", + "ax.set_yticks(major_ticks)\n", + "ax.set_yticks(minor_ticks, minor=True)\n", + "ax.grid(which='both')\n", + "ax.grid(which='minor', alpha=0.2)\n", + "ax.grid(which='major', alpha=0.2)\n", + "plt.xlabel(\"Comparison of accuracie\")\n", + "plt.show()\n", + "fig.savefig(\"Accuracy-ShakerRNAfold-SukosdMFE\"+ '.png', bbox_inches='tight')" ] }, { "cell_type": "code", "execution_count": null, - "metadata": { - "collapsed": true, - "deletable": true, - "editable": true - }, + "metadata": {}, "outputs": [], "source": [] } @@ -355,7 +372,7 @@ "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython2", - "version": "2.7.12" + "version": "2.7.11" } }, "nbformat": 4, diff --git a/notebooks/07_reactivity_value_boxplots.ipynb b/notebooks/07_reactivity_value_boxplots.ipynb index e4df5cf..afcfadb 100644 --- a/notebooks/07_reactivity_value_boxplots.ipynb +++ b/notebooks/07_reactivity_value_boxplots.ipynb @@ -4,9 +4,7 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": true, - "deletable": true, - "editable": true + "collapsed": true }, "outputs": [], "source": [ @@ -19,9 +17,6 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": false, - "deletable": true, - "editable": true, "scrolled": true }, "outputs": [], @@ -51,11 +46,7 @@ { "cell_type": "code", "execution_count": null, - "metadata": { - "collapsed": false, - "deletable": true, - "editable": true - }, + "metadata": {}, "outputs": [], "source": [ "# LOAD DATA\n", @@ -107,7 +98,6 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": false, "scrolled": true }, "outputs": [], @@ -137,7 +127,6 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": false, "scrolled": true }, "outputs": [], @@ -155,7 +144,6 @@ "cell_type": "code", "execution_count": null, "metadata": { - "collapsed": false, "scrolled": false }, "outputs": [], @@ -199,7 +187,7 @@ "name": "python", "nbconvert_exporter": "python", "pygments_lexer": "ipython2", - "version": "2.7.12" + "version": "2.7.11" } }, "nbformat": 4,