This has been mentioned by a few people on the KSP forum, where the game lags with low FPS for a while when entering flight or changing SOI.
I had a look at the code and the problem is that the BiomeFilter object is added twice, so its trying to generate the filtered biome map twice concurrently.
I've made a simple change to fix this. I'd be happy to submit a pull request for it, if you're interested.