using with anaconda, no module named pudb when vimdiff

[smilesun]

I am using vim 8, and anaconda with pudb installed,
my settings are

let g:pudb_python='~/anaconda3/bin/python'                                                                                                                                                                   
let g:pudb_python_launcher='~/anaconda3/bin/python'                                                                                                                                                          
let g:pudb_python_host_prog='~/anaconda3/bin/python'                                                                                                                                                         
let g:pudb_python4_host_prog='~/anaconda3/bin/python' 

when I run vimdiff file1, file2, i got

Error detected while processing function <SNR>108_SetInitialBreakpoints:                                                                                                                                           
line   26:                                                                                                                                                                                                         
Traceback (most recent call last):                                                                                                                                                                                 
  File "<string>", line 2, in <module>                                                                                                                                                                             
"....py" 254L, 9926C                                                                                                      
Traceback (most recent call last):                                                                                                                                                                                 
  File "<string>", line 2, in <module>                                                                                                                                                                             
ModuleNotFoundError: No module named 'pudb'                                                                                                                                                                        
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