diff --git a/.readthedocs.yaml b/.readthedocs.yaml
index 0e0a8fa5..afb0deef 100644
--- a/.readthedocs.yaml
+++ b/.readthedocs.yaml
@@ -1,17 +1,18 @@
 version: 2
 
-build:
-  os: "ubuntu-20.04"
-  tools:
-    python: "3.10"
-
-# Build from the docs/ directory with Sphinx
 sphinx:
-  configuration: docs/source/conf.py
+   configuration: docs/source/conf.py
 
-# Explicitly set the version of Python and its requirements
-python:
-  install:
-    - requirements: docs/requirements.txt
-    - method: pip
-      path: .
+build:
+   os: ubuntu-24.04
+   tools:
+      python: "3.13"
+   jobs:
+      pre_create_environment:
+         - asdf plugin add uv
+         - asdf install uv latest
+         - asdf global uv latest
+      create_environment:
+         - uv venv "${READTHEDOCS_VIRTUALENV_PATH}"
+      install:
+         - UV_PROJECT_ENVIRONMENT="${READTHEDOCS_VIRTUALENV_PATH}" uv sync --extra doc
diff --git a/docs/source/conf.py b/docs/source/conf.py
index f31fb9af..a9fa9905 100644
--- a/docs/source/conf.py
+++ b/docs/source/conf.py
@@ -12,7 +12,6 @@
 # documentation root, use os.path.abspath to make it absolute, like shown here.
 #
 from datetime import date
-from pathlib import Path
 
 import git
 
@@ -257,14 +256,4 @@
 sphinx_gallery_conf = {
     "examples_dirs": "../../examples",  # path to your example scripts
     "gallery_dirs": "auto_examples",  # path to where to save gallery generated output
-    "binder": {
-        "org": "Owkin",
-        "repo": "PyDESeq2",
-        "branch": current_commit,  # Can be any branch, tag, or commit hash.
-        # Use a branch that hosts your docs.
-        "binderhub_url": "https://mybinder.org",  # public binderhub url
-        "dependencies": str(Path(__file__).parents[2] / "requirements.txt"),
-        "notebooks_dir": "jupyter_notebooks",
-        "use_jupyter_lab": True,
-    },
 }