Standardized README to Markdown format

README.md

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+# Reconstitution of Action Potentials in a Model of a Hippocampal Mossy Fiber from Action Potential-Evoked Sodium, Potassium and Calcium Current Waveforms as Described In
+
+Henrik Alle, Arnd Roth and J. R. P. Geiger, Energy-efficient action potentials in hippocampal mossy fibers, *Science* 325, 1405-1408 (2009). doi: 10.1126/science.1174331
+
+This directory contains mod and hoc files for the NEURON simulator, as well as dat files representing the conductance waveforms which are read in via the `stepforce()` function in GNa.mod, GK.mod and GCa.mod.
+
+## To run the simulations, follow these steps:
+
+1. Compile the mod files using `nrnivmodl` under Mac OS X and Linux, or `mknrndll` under Windows.
+
+2. Run `reconstitution.hoc` in NEURON. This performs the simulation shown in Fig. 2A and B of the paper and plots the results using NEURON's graphical user interface.
+
+3. If desired you can perform an automated fit of the measured action potential waveform by running `fit_th1.hoc`. This writes results to three files: `parameters1.txt`, `measuredAP1.txt`, and `modelAP1.txt` and may take several hours.
+
+If you have questions please contact  
+henrik.alle@charite.de  
+arnd.roth@ucl.ac.uk  
+
+---
+
+2025-06-02: Converted README to Markdown.