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18 changes: 18 additions & 0 deletions Biological_Environmental/host-associated-isolates.md
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# Microbial Isolates from Mammalian Hosts

In addition to the direct analysis of microbial ecosystems using molecular techniques, cultivation-based approaches are very important for microbiota research
The isolation and characterization of strains make it possible to describe novel taxonomic and functional diversity, define the mechanisms underlying microbe- microbe and microbe- host interactions, and open avenues for biotechnological and clinical applications.
Working with isolates generates a lot of technical, environmental, and biological data and metadata that must be taken care of according to the [FAIR principles](/Research-Data-Management/04-fair).
Moreover, the use of isolates must adhere to the [Nagoya Protocol](https://www.cbd.int/abs/about). With NFDI4Microbiota, the [University Hospital of RWTH](https://www.ukaachen.de/kliniken-institute/institut-fuer-medizinische-mikrobiologie/forschung/ag-clavel/our-research/)
[Aachen](https://www.ukaachen.de/kliniken-institute/institut-fuer-medizinische-mikrobiologie/forschung/ag-clavel/our-research/) and the [Leibniz Institute DSMZ](https://www.dsmz.de/) generate public collections of bacterial isolates from the intestine of human and animals to help the community. The naming of novel bacteria improves the resolution of microbiota analysis by high-throughput molecular methods, and researchers can use the isolates for their own experiments, enabling further progress in the field.

Human intestinal bacterial collection (HiBC):
[www.hibc.rwth-aachen.de](https://www.hibc.rwth-aachen.de/)
Mouse intestinal bacterial collection (miBC):
[www.dsmz.de/miBC](https://www.dsmz.de/collection/catalogue/microorganisms/special-groups-of-organisms/dzif-sammlung/maus-mikrobiomliste)
Chicken intestinal bacterial collection (ChiBAC):
[www.dsmz.de/chibac](https://www.dsmz.de/collection/catalogue/microorganisms/special-groups-of-organisms/dzif-sammlung/chicken-microbiome)

## Credits

This section was written by Tom Cleval, [ORCID](https://orcid.org/0000-0002-7229-5595) (University Hospital RWTH Aachen).