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10 changes: 10 additions & 0 deletions .gitignore
Original file line number Diff line number Diff line change
@@ -1,4 +1,5 @@
*.tar.gz
*.npz
*.py[cod]

# C extensions
Expand Down Expand Up @@ -60,3 +61,12 @@ env.yml
# Rust stuff
Cargo.lock
target*

# snakemake
.snakemake
*.smk

# jupyter notebooks
.ipynb_checkpoints
*.ipynb_checkpoints
*.ipynb
28 changes: 18 additions & 10 deletions deeptools4.0.0_changes.md
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@@ -1,22 +1,21 @@
# computeMatrix
# Changes

## computeMatrix

- --sortRegions 'no' option no longer exists
- Sorting ascend / descend no longer has subsorting by position.
- --quiet / -q option no longer exists.
- bed files in computeMatrix no longer support '#' to define groups.
- 'chromosome matching' i.e. chr1 <-> 1, chrMT <-> MT is no longer performed.

# normalization
## normalization

Exactscaling is no longer an option, it's always performed.
- Exactscaling is no longer an option, it's always performed.

# Todo

- allow multithreaded bw writing
- properly divide region work over threads -> region sorting & taking size into account
- calc for computeMatrix functions -> Struct / Enum
- filehanlder bed file could all be &str, not clones
## alignmentSieve

- options label, smartLabels, genomeChunkLength are removed.
- ignoreDuplicates is removed, and (if wanted) should be set by the SamFlagExclude setting.

# Testing

Expand All @@ -28,4 +27,13 @@ Exactscaling is no longer an option, it's always performed.
- skipZeros
- duplicate renaming _r1, _r2, ...
- GTF, BED3, BED6, BED12, mixedBED (?)
- scaleRegions, un5, un3, regionbodylength, metagene
- scaleRegions, un5, un3, regionbodylength, metagene

## alignmentSieve

- unmapped reads to unfiltered_out

# Todo

- AlignmentSieve: Shift, Bed, Optimization.
- bamCoverage / bamCompare: filtering, extend.
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