v1.3.0

pmxTools 1.3

• Added NCA parameter estimation to calc_derived_1cpt(), calc_derived_2cpt() and calc_derived_3cpt(), if dose and other required information (e.g. tinf, dur, tau) is provided.

• Added a warning about flip-flop kinetics and their potential effects on derived half-lives to calc_derived_1cpt(), calc_derived_2cpt(), and calc_derived_3cpt().

• Added blq_trans() and blq_log_trans() for assistance with visualization of measurements below a limit of quantification.

• Added a test for valid XML to read_nm().

• Small fixes and enhancements to read_nmtable_single() and read_nm_multi_table() to ensure that stray text is properly handled while reading in NONMEM output files.

• count_na() now throws a warning if NaN values are included in the NA count, and indicates how many of them there are.

• Changed the significant digits functionality for 95% confidence intervals for get_theta(), get_omega() and get_sigma(), and all functions that apply these.

• Replaced gridExtra with patchwork.

• Numerous small fixes.

• Removed some unnecessary dependencies.

• Added many new unit tests, increasing test coverage considerably.

1.2.1

Version 1.2.1